Cytokine Production by the Murine after Exposure to Lactobacilli MacrophageCeilLine J 774 . 1 JseA

نویسنده

  • Arthur C. OuwEHAND
چکیده

ity to induce the murine macrephage-like cell line J774.1 to secrete cytokines. Some ef the bacteria tested induce the preduction of interleukin(IL) 6, IL-12, and tumor necrosis factor a (TNF-a) by J774.1 cells. Seyen strains also induced the produetion of IL-10. However, ne IL1fi was produced. LactobaciUdes acidophiltts TMC 0356 significantly induced the production of more IL-6, IL-10, IL-12, and TNF-a than the other bacteria tested (p<O.OOOI; ANOVA). These results suggest that lactobacilli can activate macrophages te secrete both inflammatory and anti-i"fiammatory cytokines. Selected strains might be used to bring about pro or antiinflammatory immune reactions.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cytokine Production by the Murine after Exposure to Lactobacilli MacrophageCeilLine J 774 .

ity to induce the murine macrephage-like cell line J774.1 to secrete cytokines. Some ef the bacteria tested induce the preduction of interleukin(IL) 6, IL-12, and tumor necrosis factor a (TNF-a) by J774.1 cells. Seyen strains also induced the produetion of IL-10. However, ne IL1fi was produced. LactobaciUdes acidophiltts TMC 0356 significantly induced the production of more IL-6, IL-10, IL-12, ...

متن کامل

T Helper 2 Cytokine Analysis of Bronchoalveolar Lavage in the Murine Model of Allergic Broncho Pulmonary Aspergillosis

Background and Aims: Aspergillus fumigatus is a sporadic fungus that causes different infections and allergies in immunocompromised patients. The allergic disease caused by this fungus is called allergic bronchopulmonary aspergillosis (ABPA). ABPA is considred important in atopic and immunocompromised individuals, which can result in inflammation and epithelial damage. Therefore, the aim of thi...

متن کامل

Absolute quantification of murine interleukine-4, interleukine- 10 and interferon-γ gene transcripts using Real Time PCR

The study of cytokines gene expression is quite important in various conditions of health and disease for the evaluation of clinical responses to new vaccination approaches. An absolute quantification is based on a calibration curve and production of standard controls to achieve more reliable results than in relative system. In this study we attempted to construct standard controls to evaluate ...

متن کامل

Fermentative Lactic Acid Production by Lactobacilli: Moser and Gompertz Kinetic Models

Lactic acid production in a batch submerged fermentation process by five Lactobacilli: bulgaricus, casei, lactis, delbrueckii and fermentum in lactose fortified whey culture were investigated. Kinetic behavior of Lactobacilli growth rate and lactose utilization was studied based on the Moser and Gompertz kinetic models. Trendline tool in Excel software was applied for fitness assessment of the ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2018